﻿IX, B, 6 Concepcion: Observations on Mango Rash 513 



made to appear and disappear by discontinuing and renewing the 

 mango feeding, it can be concluded that the etiology of these 

 rashes is to be ascribed to the fruit itself. 



The rash observed on the mother after mango eating is of 

 the papulovesicular type with small papules and vesicles. These 

 are characterized by more or less persistence of the lesions, 

 marked itching, and absence of other subjective symptoms. The 

 size of the papules and vesicles varies from that of a pinhead to 

 about 2 millimeters in diameter. They are round or sometimes 

 oval in shape, and appear in patches. The rash must be classed 

 as an erythema and not as urticaria. The commonest places for 

 the rash to develop are on the mammary regions, the neck, and 

 the extensor surfaces of the upper extremities. The eruptions 

 found on the baby are generally of the maculopapular type. In 

 some instances, the papulovesicular type can also be found. 

 They appear usually either singly or in patches. Their shape 

 is circular, and they are comparatively larger than those found 

 on the mother. The lesions are also less persistent, as compared 

 to those in the mother, and are less irritating. They generally 

 develop on the face, the neck, and the extensor surfaces of the 

 extremities and not infrequntly on the back. 



Other points of interest in connection with these observations 

 may be mentioned. In all of the above cases, except one (case 

 II), rashes were produced in both mother and child; this excep- 

 tion indicates that individual susceptibility is a factor in the 

 development of the rash. After successive days of feeding, the 

 mother may acquire some degree of immunity or tolerance, as 

 shown by case III, in which renewal of the mango feeding 

 failed to produce a second rash. The rashes have appeared on 

 the babies whenever mangos were given to the mothers. The 

 babies, therefore, seem to be more susceptible than are the adults. 



In conclusion, I wish to express my thanks to Prof. R. B. Gibson 

 for his suggestions and help in carrying out these observations. 

 My thanks are also due to Dr. M. Tolentino, of the department of 

 obstetrics of the Philippine General Hospital, who secured the 

 patients for the experiments. 



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