462 J- Lindhard. 



wakened in the morning; in une patient wlio obstinatelj' denieil all sub- 

 jective symptoms, objective signs of sickness were observed on the 

 3rd day. 



Amongst the first s y m p t о m s appearing were drowsiness, slug- 

 gishness, indisposition or irresistible desire to sleep; this was noted in 

 7 cases, of which however 2 must be regarded as doubtful. During the 

 first night however the sleep of most was uneasy and brokon: one 

 patient had absolutely no sleep for the first two days. 



One of the first and most constant symptoms, occurring in 18 of 

 the 19 eases, was headache. It was described by almost all as deep- 

 seated, hammering or boring pains, by a few as tension or pressure; 

 it grew worse by moving the head, coughing, sneezing etc. — and the 

 pain then spread sometimes to other regions. The pain was localized 

 in 14 cases on the forehead as the primary and main locality; mure 

 closely restricted to the lower part of the forehead, the root of the nose 

 and the part over the eyes; from here it spread out on the temples up 

 to the top of the head or in a single case to the occipital region. In se- 

 veral cases this in the beginning strictly local pain gradually became 

 more diffuse as it passed ofT. Pain only in the temples was noted in 

 one case; the first pains on the top of the head spreading later also to 

 the forehead in 3 cases. The pains were persistent, in no case par- 

 oxysmal; they seemed in all cases to culminate after about 12 hours, 

 then decreasing regularly perhaps with a little accentuation in the even- 

 ing. After the 3rd day only a few were still feeling pain with sudden 

 movements of the head. 



In a single case there was a very great sensitiveness to 

 pressure on the integuments of the head, in two cases sensitiveness on 

 the muscles of the neck. There was likewise sensitiA'eness to pressure 

 on the eyeballs (4 cases) or pain on moving these (6 cases). 



In some of the patients disturbance of the senses occurred ; in 1 case 

 double sight, in 1 case flickering which made reading impossible, in 1 case 

 a sensation of great clearness without definite colour, only that all 

 objects were seen much more distinctly than usual; lastly in 2 cases red- 

 dish-yellow or yellowish flame-sensations, the one of these very strongly 

 and troublesome, the attack lasting some minutes and accompanied 

 likewise with some pain in the eyeballs (the patient (the surgeon) had 

 experienced similar phenomena several times, but very much weaker 

 and only momentarily, about a month before after hard use of the eyes 

 in bad light). 



Tonic and clonic attacks of с r a m p occurred in 3 of the pati- 

 ents; in all 3 cases in the lower extremities and twice restricted to these; 

 in the third case the musculature of the body and upper arm was also 

 attacked in succession. The attacks occurred intermittently especially 

 in the night, lasting variously from 10 minutes to half an hour and the 

 patient was afterwards very tired. 



