56 G. F. Barker—Physiological Chemistry. 
months, dried at 212° F., 1-3 grains of amyioid substance were 
obtained, An examination of the same weight of tissue from 
a nearly full-grown foetus, gave an amount too small to be es- 
Eanten, If the t ual from a series of foetal lambs of differ- 
gradual i increase of the coloring up ain perio in- 
tra-uterine life, and then its ‘pgempeatea from that point, is 
well exhibited. In the dig the maximu ount is foun 
amyloid matter; this substance constituting more than 5 
per cent of the dry residue. Betore the animal has drawn its 
pat breath, however, it has all disappeared. In ne? 
uscle, the ‘amount is not as uniform; and, though it dimi 
Fe before birth it does not entirely anes since cha 
tary muscle can hardly be said to reach maturity at birth. 
The muscle of the heart, however, which attains maturit 
earlier than any other muscular tissue, loses its amyloid mat- 
be earlier. The amyloid substance in the liver increases up 
o and after birth, though it does not make its appearance in 
that organ until a late period, The quantity is small even at 
birth, being only two per cent in a foetal lamb 20 inches long. 
The rapidly-growing horn of a young stag, on the other hand, 
contained no amyloid matter, nor did the horn of a calf; the 
hair bulbs of adults do not contain it, nor is it to be detected 
in the new muscular fibres of the uterus after delivery. It 
does not change into sugar during foetal life, nor’ does it give 
rise to fat ; it seems rather to be a formative material which, 
uniting gradually with ana gives origin to the azotized 
structu 
1865.* With em however, some new facts were given. 
His experiments show that with animals living on their usual 
food, and apparently healthy not only the weight of the liver 
varies considerably as compared with that of the entire body, 
but the proportion of ore matter in this organ also varies 
greatly, as is shown in the following table, which Gare the mean 
of six experiments upon each kind of animal : 
: Weight of liver compared Proportion of 
gcc '.. ‘with that of entire body. amyloid matter. 
‘ as :30 4°5 
Cate, “s 1:19 15 
Rabbits, “ 1:35 3°7 
Pigeons, és 1:44 ' 2-5 
Guinea pigs “ 1:21 1-4 
Rats, " 1:26 2°5 
Hedgehogs, ‘‘ 1:27 13 
