Uric Acid^ and their derivatives. 



thus viewed with the above formula for biuret will show how 

 the latter is produced by the action of ammonia upon ethyl 

 allophanate. From acetic acid, C^H^Oa, we have acetyl-urea, 

 CgHgNaOa (exhibiting neither acid nor basic character), 

 Acetic acid (monobasic). Acetyl-urea. 



H H— N— H 



.-U 



LO-H 



u U H— C— C 



the one basic atom of hydrogen of the original acid having 

 been replaced by the urea residue at its imide extremity. 

 ^ I glycollic acid, C,: " ^ 



nd, 



Glycollic acid (monobasic). Grlycoluric acid (monobasic). 



H-U 



have glycol uric (hydantoic) 

 ■N— H 



U 



the urea residue replacing the methylic hydroxy 1, while th 

 ongmal oxatyl remains unaffected and the acid character : 

 preserved. In the formula for glycoluric acid proposed b 

 Gibbs, viz: (misprinted in his paper in the transposition < 

 the — and = in the bottom line) : 



Glycolui 



<U-=, 



the mono-basic character is not obvious, nor does it readily 

 appear which is the replaceable (basic) atom of hydrogen. 



If glycollic acid be diflferentlv conjugated with urea, the 

 residue of the latter attaching "'itself in place of the basic 

 hydroxy 1, and a molecule of water being eliminated, we get 

 hydantoiue, C3H,N,0j, (1). 



