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4. Experiments with embryos:— 
Embryos of the three species kept in saline and tap water 
respectively, were added to sterilized horse-dung or sawdust and 
placed on shaved areas of the skin of the two horses. 
. In no case was any reaction produced in the skin of the 
animals. 
5. Summary and discussion of the experiments : — 
a penetration was produced. 
Larvae of H. muscae possessed the power of making er 
way into the subcutaneous tissues, but only a very slight 
tissue reaction was produced, and this quickly disappeared. 
When they were added to the conjunctival sac they produced 
no reaction. The larvae did not appear to be capable of 
penetrating the lightly scarified skin, nor the moistened, 
uninjured skin. 
Larvae of H. megastoma produced a typical granuloma 
‘occurring under natural conditions. Those larvae that were 
not rapidly destroyed and removed produced typical necrotic 
areas in which the degenerating larvae persisted for some 
stoma and H. megastoma were comparatively small, and 
Showed little aiy. Likewise, the conjunctivitis uced 
by the larvae of H. megastoma was not of a very severe 
Character The larvae of H. megastoma, when they produced 
to be better preserved than those of 
