110 
H. microstoma found in the granulomata produced by the 
latter. . 
Under the conditions of the experiment the embryos of 
all three species appeared to be incapable of penetrating the 
skin of the horse. : 
In these later experiments the results obtained in the 
preliminary experiments were confirmed, viz. ; larvae of H. 
muscae produced no conjunctivitis and no typical granuloma 
in the skin, and the larvae of H. megastoma produced no 
typical granuloma in the skin of the pony. 
The experiments have shown that the larvae of all three 
Considering the number of larvae inoculated, is: 
number of necrotic areas produced was small. This appea 
larvae. Tissues removed from five to six hours after ne 
tion with larvae have shown the larvae surrounded iN 
neutrophile leucocytes, which attack and apparently quic e 
remove them. Some of the larvae, ds 
These neutrophile leucocytes are not found in the n: 
removed from five to seven days after inoculation. The dd 
that certain larvae of the same species appear to offer mo 
Discussion. , 
That these larval Nematodes are the cause of the granu 
lomatous reaction there appears to be no possible doubt. m 
Micr oscopical examination demonstrates that the larv ; 
od 
he site. all 
„cause a tumefaction of the tissues which later usua Y 
