115 
tissues, it is not possible to say that it is never responsible for 
the production of a habronemic granuloma. 
linical and experimental observations suggest that the 
production of a habronemic granuloma depends in some 
the particular species present. 
th Experimentally i& has been shown, for example, that 
e presence of larvae of Z. microstoma in the subcutaneous 
S 
ik Dite ri possible, further, that certain tissues may react 
citum a way as to produce a habronemic granuloma, while 
Bie vem in the same animal show no such reaction. The 
ix eo H . megastoma, for example, may set up a habronemic 
a "en Mie but when present in the subcutaneous tissues 
e same animal little or no reaction is produced ( vide 
experiments). j 
hs mete | that larvae of H. megastoma are responsible 
e production of habronemic granulomata, it seems 
likely s a ties o im deciles are more 
Hiti pn uce these lesions than other varieties. Certain 
“pemp or example, may possess more vigour 1n penetrating 
ostes membranes: or moist surfaces, or they may possess 
r powers of adaptation. The same may be true for the 
Tt is possible that habronemic granulomata may be due 
m orded species of Habronema, 
M ame and that in the final larval stage the larvae of 
Speci 
Possible that S. calcitrans may be the intermediate host of 
R other species of Habronema, the larva of which shows 
longitudinal ridges in the cuticle; but there is probably no 
