2M. 
128 
believes that the clinical form of the malady may be in agree- 
ment with the stage of evolution of the parasite. xi 
ere appears to be very little evidence to suppo 
Railliet's theory, viz., that the lesions are due to the p 
tion of the skin by embryos which develop as erratic PAM 
in an abnormal situation in undergoing an analagous deve op 
ment to that which they accomplish normally in the body ke 
thefly. It has been shown experimentally that the final es 
stage can produce a typical reaction, so, at least, this aberran 
development does not a r to be necessary. : 
3 is possible that eiecti may either penetrate the skin 
or become lodged in sores, where they may set up a pose 
reaction, but there is no experimental evidence to suppo 
this assumption. p 4 
Even if we assume the possibility of omiy D 
Habronema setting up a certain type of lesion in the X 
there appears to be little or no evidence to suggest that P 
embryos are capable of developing through their larval peue 
in this situation. Further, there is no proof that the em dud 
found by Ercolani in the one case, and by Buffard in the other, 
are embryos of Habronema. : fiac a 
Embryos of Habronema are to be found 1n the faec : 
all times of the year. If these embryos leave the oar pe 
in penetrating the skin and their subsequent evolution t Zo: 
up a typical “summer sore," it is difficult to explain ( ) fox 
seasonal occurrence of the tumours and (2) the massive 1n 
tion at one point. : is of 
The life-history of the three species of H abror de 
that type which involves a simple alternation betwee: 
: al 
inve te harbouring the larval stage. From 4 Ls wane 
nsideration it seems reasonable to assume that 1t 1s 1 dii 
able, should this alternation be broken, that the worm 
able to carry on its development. To NATUS 
Before Railliet’s theory can be accepted it will require 
support of more clinical and experimental evid 
The 
Eer 
ence. : 
inconstant parasite" of Descazeaux, believes ie 
