Va eer, 
386 . G. F. Barker—Physiological Chemistry. 
a hee | 
obtained. The ex; t was repeated many ti 
with the same result. 
18 
yy? 
24th of September, he recapitulates the grounds on which he 
in the liver from fibrin or hematin, and of Frerichs that ni- 
trogenous matters break up in the liver into urea and sugal— 
all of which views suppose the change to take place in the 
blood,—he advances the opinion that the glycogenic sub- 
stance exists in the tissue of the liver itself. This view hesus- 
tains by the following experiment: a vigorous and healthy dog, 
fed for many days exclusively upon meat, was killed by section 
of the medulla, seven hours after a full meal of tripe. The 
abdomen was immediately opened, the liver carefully removed, 
and while yet warm, before coagulation of the blood had taken 
place, the portal vein was connected with the laboratory hydrant 
by means of a rubber tube, and water allowed to flow throug 
the organ, escaping from the hepatic veins in a strong Je : 
Gradually the tissue of the liver became paler, andin 15 mi rae 
utes the water was colorless, After 40 minutes, the escapMG = 
water contained nota trace either of sugar or of albummolé 
matter; and on macerating a fragment of the viscus, no Sug 
was detected in the tissue. The liver was then allowed tote 
| 
: 
| 
main exposed to the air for 24 hours, after which time et ak 
isted in it abundantly; even a little liquid remaining in the OS 
gave the reactions; and on injecting water into the portal her 
it issued strongly saccharine. The liver must therefore eae | 
sufficiently 7 
; is, which, 
in alcohol and ether; and showed that it is confined strictly 
* C.R., xli, 461. E 
