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A CONTRIBUTION TO THE STUDY OF H ABRO N EM I ASI S : 

 A CLINICAL, PATHOLOGICAL, AND EXPERIMENTAL IN- 

 VESTIGATION of a Granulomatous Condition of 



THE HORSE-HABRONEMIC GRANULOMA. 



By Lionel B. Bull, D.V.Sc, 



S.A. Government Laboratory of Pathology and Bacteriology, 



Adelaide Hospital. 



[Read August 15, 1919.] 

 Plates XIII. to XV. 



Contents. 



A. Introduction. 



B. Granulomata as found in Southern Australia. 



Clinical : — Distribution ; Occurrence ; Site ; Duration ; 



Examination. 

 Pathological : — Microscopic examination ; Macroscopic 



examination. 

 The larval Nematode. 

 Observations on the Life-histories of the Three Species 



of Habronema: — Habronema muscae, H. megastoma, 



H. microstoma. 

 Animal Experimentation. 



1. Habronema microstoma — 



(a) Feeding experiments with Stomoxys calcitrans. 



(b) Larvae placed in the skin of the horse. 



(c) Larvae placed on scarified skin. 



2. Habronema muscae — 



(a) Larvae placed in the skin of the horse. 



(b) Larvae added to the conjunctival sac. 



(c) Larvae placed on scarified skin. 



(d) Larvae placed on moistened skin. 



3. Habronema megastoma — 



(a) Larvae placed in the skin of the horse. 



(b) Larvae added to the conjunctival sac. 



(c) Larvae placed on scarified skin. 



(d) Larvae placed on moistened skin. 



4. Experiments with Embryos. 



5. Summary and Discussion of Experiments. 

 Discussion. 



C. Granulomata as found in Northern Australia. 



General ; Pathological ; Discussion. 



D. Similar Granulomata as found, outside Australia. 



1. "Summer Sores." 



2. "Swamp Cancer" in the Solomon Islands. 



3. "Leeches" and "Bursattee." 



E. Nomenclature. 



F. General Summary. 



G. Prophylaxis and Treatment. 

 References to Literature. 



. Description of Figures. 



