SPUTUM SEPTICEMIA. 321 



bacillus septicus spvtigenus, diplococcus lanceolatus eap- 

 sidatus, micrococcus pneunionioe crouposa. 



b. A form of septicaemia resulting from invasion 

 of the tissues by an organism frequently seen in the 

 sputum of tuberculous subjects. It is characterized 

 by its tendency to divide into fours. It is micro- 

 coccus tetragenus. 



c. Local or general tuberculosis. 



a. SPUTUM SEPnc^iiiA. 



If at the end of twenty-four to thirty-six hours the 

 animal be found dead, we may reasonably predict that 

 the result was produced by the introduction into the tis- 

 sues of the organism of sputum septicaemia above men- 

 tioned, viz., micrococcus lanceolatus, which is not uncom- 

 monly foimd in the mouths of healthy individuals as 

 well as in other conditions. 



Inspection of the seat of inoculation usually reveals 

 a local reaction. " This may be of a serous, fibrinous, 

 hemorrhagic, necrotic, or purulent character. Fre- 

 quently we may find combinations of these conditions, 

 such as fibro-purulent, fibrino-serous, or sero-hemor- 

 rhagic." * The most conspicuous naked-eye change 

 undergone by the internal organs wiU be enlargement 

 of the spleen. It is usually swollen, but may at times 

 be normal in appearance. It is sometimes hard, dark 

 red, and dry ; or it may be soft and rich in blood. Fre- 

 quently there is a limited fibrinous exudation over por- 

 tions of the peritoneum. 



Except in the exudations, the organisms are found 

 only in the lumen of the bloodvessels, where they are 



• Welch : Johns Hopkins Hospital Bulletin, Decemher, 1892, vol. iii. 

 No. 27. 



•21 



