152 MICRO-ORGANISMS AND DISEASE [chap. 



1886 to the Local Government Board). This intimate 

 relation between an eruptive (ulcerative) disease of the teats 

 and udder of milch cows to the cause of human scarlet 

 fever was subsequently to 1886 demonstrated in several 

 other localities (Glasgow, New Cross). In the Hendon 

 cows, above referred to, there was in addition disease of 

 the lungs and kidneys, from which the streptococcus was 

 obtained by culture. Cultivations of the streptococcus 

 from the blood of human scarlet fever or from the eruption 

 on the teats of cows produced in mice and calves a 

 definite general infection ; in healthy milch cows the injec- 

 tion of the streptococcus produced the eruption with sub- 

 sequent ulceration on the teats and udder, as also the 

 visceral disease observed in the Hendon cows. {Reports 

 of the Medical Officer of the Local Government Board for 

 1886, 1887, 1888.) 



8. Loffler 1 showed that in faucial diphtheria, and asso- 

 ciated with the diphtheria bacilli, occur streptococci, some 

 of which, at any rate, play an important part in the secon- 

 dary infections — swollen and suppurative glands — as also in 

 septicemic infection. These streptococci when injected into 

 animals cause occasionally disseminated inflammatory foci, 

 principally*n the joints, and general septicsemic infection. 



9. Membranous exudations in, and inflammation of, the 

 fauces occur which are not accompanied by diphtheria 

 bacilli, and which therefore are not true diphtheria ; they do 

 not lead to post-diphtheritic paralysis and terminate in 

 recovery; they resemble mild cases of diphtheria. Such 

 cases represent the cases of pseudo- or cocco-diphtheria. The 

 exudation is found to be crowded with cocci, often in 

 larger or smaller masses, numerous leucocytes being also 

 present. When cultivated one obtains colonies of staphylo- 



' Miltheihingen aus d. k. Gesundheilsainte, II. 



