232 MICRO-ORGANISMS AND DISEASE [chap. 



of the above case were found in the blood, in the peri- 

 cardial exudation, in the juice and in the bloody fluid filling 

 the alveolar cavities of the inflamed lung, in the vessels of 

 the kidney, in the submucosa of the inflamed Peyer's 

 glands of the small intestine, and in the blood-vessels of 

 the spleen and around them. 



The bacilli vary in length between 0-003 and 0-009 ro™- > 

 their thickness is about o"ooi3 mm. They are rounded at 

 their extremities, single or in chains of two, and some con- 

 tain a bright oval spore, situated in the centre or at one end, 

 and about o'ooi mm. thick. This was the case with the 

 bacilli in the glomeruli of the kidney of the Welbeck case. 

 The bacilli containing spores were thicker than those without 

 them. 



Experiments by feeding and inoculation made on dogs and 

 cats, rabbits, guinea-pigs, and mice with the ham that had 

 done the mischief in the Welbeck case produced positive 

 results. In all cases we found pneumonia and hemorrhage 

 in the liver, peritonitis in some, spleen enlarged in most. 

 The bacilli found in this ham were cultivated in the incubator 

 in white of egg, and after two days' cultivation four white 

 rats and several guinea-pigs and white mice were inocu- 

 lated, and they became ill after twenty-four hours ; they 

 were quiet, did not feed well, and were more or less 

 soporous. When killed the spleen was found enlarged, 

 and in the lungs were found haemorrhage and hyperaemia, 

 and in some cases extensive pneumonia. 



Blood, pericardial exudation, and lung juice from the 

 fatal Nottingham case inoculated into ten animals (guinea- 

 pigs and white mice) produced fatal results in six, the other 

 four were killed : but in all there was severe pneumonia, in 

 eight out of the ten there was peritonitis, in four also 

 pleuritis, and in two in addition enlargement of the liver 



