238 MICRO-ORGANISMS AND DISEASE [chap. 



is drawn that typhoid fever is not a blood disease ; that is to 

 say, the blood is not the proper soil for the growth and 

 multiplication of the microbe, but the wall of the ileum, 

 the spleen, and mesenteric glands (and possibly other lymph 

 glands) represent the localities wherein the bacillus grows and 



Fig. S5, — A TVPic.-\L Gelatine-Platf, Cultivation of the Tvi'HOid Bacillus ; 



THE SMALL DOTS ARE DEEF CoLONIES, THE PATCHES AKE COLONIES ON 



THE Surface: the Culture is about 6-7 da\-s old and shows the 



CONCENTRIC MARKINGS OF SUPERFICIAL COLONIES. 

 N.iturnl siz^. 



multiplies and produces the toxin (typhotoxin) which causes 

 the symptoms of the disease. Thus typhoid fever would in 

 reality be the result of intoxication in its chief clinical 

 symptoms. Owing to the fact that the demonstration of 

 the typhoid bacillus in the typhoid stools, because of our 



