XI] BACILLI : SPECIFICALLY PATHOGENIC 239 



at present imperfect methods, is in many cases negative, 

 Sanarelli has come to the conclusion that the pathological 

 changes of the intestine are as much a result of the toxin 

 action of the bacillus distributed in the blood and viscera as 



Fig. 86. — Three Tuise-Plate Cltlti\'ation's of the Tvi'iioin Bacillus: 



COLON'IES ON THE SURFACE OF GELATINE. In THE LEFT Tui!E THE COLONIES 

 ARE VERY NUMEROUS, P.MALL, AND IN THE LOWER PART CONFLUENT ; 

 IN THE MIDDLE TUBE THE COLONIES ARE FEWER AND LARGER; AND IN 

 THE RIGHT Tl:BE ONLY ONE COLONY OF tlREAT Sl2E, AND SHOWING THE 

 CONCENTRIC ASFECT. 



Compare this figure with Fig. 60 of .similar cultures of bacillus coli. 

 Natural size. 



are the other clinical symptoms. Wright and Semple ^ have 

 attempted to give support to this theory of typhoid fever 

 being really a blood disease by stating that in all, or almost 

 all, cases which they have examined — some of them early 



1 The Lancet for July 27, 1S95, 



