xii] PATHOGENIC BACILLI : GROUP C 253 



injected and oedematous; the Payer's glands are swollen, the 

 spleen and liver are much congested and slightly enlarged. 



The blood of the heart, and particularly the juice of the 

 lymph glands and the spleen, contain fine baciUi very similar 

 to those of the mouse septicaemia (Schiitz) (o"6- 1-8 fj. long). 

 On microscopic sections through the liver, spleen, kidney, 

 and lymph glands the bacilli are easily demonstrated in the 

 capillary blood-vessels, either isolated between the blood 

 corpuscles or enclosed in the swollen leucocytes. As re- 

 gards cultural characters they completely resemble those of 

 the mouse septicsemia (Koch). 



Swine fed or inoculated with the blood or tissues of a 

 pig dead of the disease become also affected. Mice ^ 

 and pigeons are very susceptible to the disease ; guinea- 

 pigs and fowls are refractory ; rabbits show generally only a 

 local effect ; mice die in two or three days, pigeons in three 

 to four days ; in both the blood of the general inoculation 

 and of the organs contains abundantly the bacilli. In the 

 pigeon numerous white blood-corpuscles in the vessels of 

 the viscera are filled with the bacilli. 



Pasteur has shown that the virus in its passage through a 

 series of pigeons increases in virulence, both as regards the 

 pigeon as well as the pig ; on its passage through a series of 

 rabbits it increases in virulence as regards the rabbit, but 

 decreases in virulence as regards the pig. Pigs inoculated 

 with blood of the last rabbit of the series become ill, but 

 recover, and are then found refractory to inoculation with 

 the virulent disease. 



3. 2^/te bacillus of Egyptia7i ophthalmia catarrhal con- 

 junctivitis (Koch). — Koch [Chokrabericht, 1883) has shown 



^ Mice die with congested and enlarged spleen, greatly congested 

 lungs ; the intestines are relaxed and filled with sanguineous mucus ; 

 the kidney and liver are enlarged and congested. 



