332 MICRO-ORGANISMS AND DISEASE [CH. xni. 



ever, not admitted by many observers. Alvarez, Paltauf 

 and Von Eiselsberg, Wolkowitsch and Dittrich found these 

 bacilli also in the lymphatics of the surrounding tissue. 

 Paltauf and Von Eiselsberg, then Dittrich, Babes, and others, 

 produced in guinea-pigs, mice, and rabbits a septicajmic 

 infection similar to that producible by Friedlander's bacilli, 

 but no chronic nodular disease. 



The constant presence, then, of the capsulated rhino- 

 sclerom bacilli in the scleromatous tissue, particularly the 

 Mikulicz cells, is a fact of which there can be no doubt, but 

 it is equally a fact that they are identical with the bacilli of 

 Friedlander ; their causative relation to the rhinoscleroma- 

 tous process is, therefore, more than doubtful, or at any 

 rate not sufficiently supported. 



