BACILLUS TUBERCULOSIS 



361 



tuberculin in lupus, bone tuberculosis, and in early pul- 

 monary tuberculosis ; in advanced pulmonary tuberculosis 

 the injection of tuberculin has in some cases produced a 

 dissemination of the tubercle bacilli and acute miliary 

 tuberculosis in the lung and other viscera (Virchow). The 

 same or similar results had been obtained in tuberculised 

 guinea pigs by Baumgarten after injection of tuberculin. 



-From a Section through Leprous Skin, showing numerous 

 Leprosy Bacilli in Cells and between them. 



With Koch's tuberculinum a large number of observations 

 have been made in all countries as to its diagnostic value in 

 bovine tuberculosis, and the result is overwhelmingly in 

 favour of it, since by the positive reaction (raised tempera- 

 ture and constitutional disturbance) produced in a given 

 animal after subcutaneous injection of tuberculinum, it is 

 possible to diagnose tuberculosis even when other (physical 



