484 MICRO-ORGANISMS AND DISEASE [chap. 



dependent on such acclimatisation, and are not ordinary 

 moulds, but a distinct species of aspergillus (Lichtheim), 

 which grows well at higher temperatures (38° to 48° C), 

 and the spores of which under all conditions of growth are 

 capable of producing in rabbits the mycosis in question. 



Several cases of aspergillus infection in man (Pneumono- 

 mycosis) have been recorded, see R. Boyce, Journal of 

 Pathol, and Baderiol., No. 2, 1892. 



(c) Pe7iicillium. — In this fungus hyphae, which are not sep- 

 tate, grow out from the mycelium ; from the end of each of 

 these arise like the fingers of the hand a number of short 

 branched cylindrical cells, which give origin to chains of 

 spherical spores. 



The following two fungi belong to the order of fungi 

 called Phycoviycetes. 



(d) Mucor is characterised by this, that from the mycelium 

 hyphcB grow out which are not septate, and at the end of 

 these a large spherical cell originates, sporangium, in which 

 by endogenous formation a large number of spherical spores 

 are developed ; the wall of the sporangium giving way, the 

 spores become free. 



An important case of general "mycosis mucorina" in 

 man, ending in death, has been recently described by Dr. 

 Paltauf {Virchow's Archiv, vol. 102, 3, p. 543). From the 

 alimentary canal of the patient an invasion of the internal 

 organs by the mycelium and spores of a kind of mucor 

 occurred, leading to the formation of metastatic inflam- 

 matory foci in the Peyer's glands, lungs, pharynx, larynx, 

 cerebrum, and cerebellum. In these organs were found foci 

 of inflammation caused by mycelial threads and sporangia, 

 belonging to the group of mucor. Mucor rhizopodiformis 

 and corymbifer were shown by Lichtheim to be pathogenic 

 when injected into the vessels of the rabbit. 



