503 MICRO-ORGANISMS AND DISEASE [chap. 



been signalised already by Golgi, viz., a crescentic form ; but 

 also here the commencement of the attack is characterised by 

 the amceboid endoglobular forms, and the life cycle of the 

 parasite becomes completed by the division of it into sporules. 



Danilewsky, Grassi and Feletti, Kruse, Pfeififer, Celli and 

 Sanfelice, and others describe the occurrence of similar 

 parasites in the red blood-corpuscles of a number of 

 different animals, frogs and birds (see Fortschritte d. Med., 

 Band ix., Nos. 12 and 13, 1891). 



2. Amceba Coli of dysentery. — Losch ( Virchow's Archiv 

 f. pathol. Anatomie, 1875, Band Ixv., p. 196) was the first 

 who discovered the amoeba coli in great numbers in a case 

 of ulcerated large intestine in the human subject. This 

 case, in all its clinical and pathological symptoms, resembled 

 true dysentery. 



Kartulis (Centralbl. fiir Bad. und Farasit, vii., 2) has 

 shown that in the cases of tropical dysentery which he 

 examined there were present in the characteristic sanguineous 

 stools numerous amceba (amoeba coli of Losch) showing 

 active amceboid movement, and he gives good reason for 

 considering these the cause of the dysentery, though others 

 who had met with similar amoeba in intestinal diseases in 

 Russia (Massiatin, Centralbl. fiir Bad. und Parasit, vi., 

 Nos. 16 and 17) did not think so. 



Further, Kartulis has shown that in twenty cases of 

 abscess of the liver complicating dysentery he found in 

 every one of them the same dysentery amobae ; they could 

 be seen in sections through the wall of the abscess, but in 

 the pus of the abscess cavity he did not find them. 



A considerable amount of literature exists at present on 

 the occurrence of amoebae in certain forms of dysentery, 

 chiefly those that run a chronic course, and on their absence 

 and the presence of various species of bacilli in other 



