364 BACTERIOLOGY. 



The liver frequently contains opaque, whitish or yel- 

 lowish-white spots and streaks of irregular size and 

 shape, which give a peculiar mottling to the organ when 

 present in large number. These areas may be numer- 

 ous, or only one or two may be found. In size they 

 range from minute points to areas of from 2 to 3 cm. in 

 extent. 



By microscopic examination they are found to repre- 

 sent places where the liver cells have undergone necrosis 

 accompanied by emigration of leucocytes, and the cells 

 about them are in a condition of fatty degeneration. 



In sections of the liver masses of the bacilli may be 

 discovered in and about the necrotic foci just described. 



At these autopsies the colon bacillus is not found 

 generally distributed through the body, but is only to 

 be detected in the bile, liver, and occasionally in the 

 spleen.^ 



^ Consult paper by Blachstein on this subject. Johns Hopkins Hospital 

 Bulletin, July, 1891. 



