Diseases of the Liver and Spleen. 107 



in the detection of the same elements which had been ob- 

 served in the former case. , 



" No history was obtained in either instance, but there can 

 be no dpubt that the primary deposit occurred in the me- 

 sentery in the first case, and in the spleen in the second, 

 and that it was followed in both by cancerous infiltration into 

 the structure of the liver." 



BILIARY CALCULI. 



These are not unfrequently met with in canine practice, 

 and, as already stated, are one of the causes operating in 

 the production of jaundice. 



Symptoms. — The presence of biliary calculi is, as a rule, 

 unattended with pain so long as their substance is small, 

 and they can pass through the ducts without distending 

 their walls ; when, however, they become fixed, the pain 

 is usually severe, and its seat denoted by the animal look- 

 ing rotind towards the region of the liver, moaning and 

 lying on the opposite side. Excessive vomiting and tor- 

 pidity of the bowels, with flatulency and hiccup, attend this 

 biliary impaction. When complete blocking of the duct 

 takes place the bile is retained, and consequently re-ab- 

 sorbed — hence jaundice. The faeces are nearly white, the 

 urine of a deep orange colour. The pain is of a colicky 

 nature ; there is no inflammatory fever, increased respira- 

 tion, or disturbed pulse, and the passage of calculi once 

 effected, a restoration to usual health follows. 



Treatment. — This chiefly consists in relieving the pain 

 during the passage of the calculi. Opium or aconite are 

 the agents best adapted for this purpose ; r to 2 grains of 

 the former, or i to 3 minims of the latter, every three hours. 

 With regard to the administration of solvent agents for 

 biliary calculi, nitro-muriatic acid, sulphuric ether, and 

 carbonate of soda are each advocated and may be tried, 

 but there is no direct proof that in passing through the 



