Diseases of the Netvous System. 257 



some of the pathological alterations were so frequent that 

 they could be accurately grouped, yet others were so in- 

 constant that there could not be said to be any certain 

 indication of the presence of the disease. In some were 

 found alterations in the brain ; in others, changes in the 

 blood, lymphatic glands, and kidneys ; and in others, 

 morbid manifestations in the digestive organs were met 

 , with. The malady prevailed as an epizooty, and animals 

 of both sexes, various ages and breeds, when or whether 

 bitten often unknown, were at different times brought to the 

 Institute. Frequently little could be learned with regard 

 to the animals which were brought dead, and even their 

 condition previous to death could rarely be ascertained. 

 With regard to the value of some pathological alterations 

 in forming a judgment as to the presence of the disease, 

 the following epitome is given of the result of the necrosco- 

 pical examinations made of these animals : 



a. Alterations in the brain, i. Haemorrhage into the 

 subcutaneous tissue of the cranium of a suspected dog. 

 2. Haemorrhage irito the dura mater of two rabid and one 

 suspected animals. 3. Injection of the pia mater and 

 plexus chorides in 28 rabid and 2 suspected. 4. Hyperaemia 

 of the brain in 2 rabid. 5. Softening of the brain in various 

 degrees — from mere shining softness (glazend und weicker 

 sein) to complete pulpy liquefaction — in 35 rabid and 2 

 suspected animals (of these the whole brain was generally 

 involved in 3 rabid cases ; the cerebellum in 3 rabid, and 

 2 suspected ; the upper surface and base of the brain in r 

 rabid animal. 6. Distension of the lateral ventricles, 

 through a collection of serum therein, in 10 rabid animals, 

 I of which had the right ventricle unusually dilated, while 

 the left was normal. 



b. Alterations in the circulatory apparatus and the blood. 

 I. Pericarditis in I suspected dog. 2. Capillary haemorrhage 

 into the pericardium in 2 rabid cases. 3, Haemorrhage 

 beneath the endocardium in i rabid case. 4. Alterations 



