262 The Management and Diseases of the Dog. 



Kolesemkoff reports the results of the examination of ten 

 mad dogs made in Rudneffs pathological laboratory at 

 St. Petersburg. The parts examined were the cerebral 

 hemispheres, the corpora striata, thalami optici, cornua am- 

 monis, cerebellum, medulla oblongata, medulla spinalis, and 

 the sympathetic and spinal ganglia. The changes were 

 always most marked in the ganglia, and were as follows : 



1. The vessels were much distended and filled with red 

 corpuscles. Here and there along their course were seen 

 groups of red corpuscles, and round indifferent elements 

 (probably emigrated white corpuscles) scattered in the 

 perivascular spaces. The walls of the vessels were spotted 

 with hyaloid masses of various forms, sometimes extending 

 and obstructing the lumen of the vessel-like thrombi. Not 

 far from these were collections of white and red corpuscles. 



2. There was found to be a collection of round, indifferent 

 elements in general around the nerve-cells, sometimes 

 penetrating into the protoplasm of the cells to the number 

 of five or eight ; sometimes in such number as quite to 

 displace the cell-protoplasm. he number of migrated 

 cells produced various changes in the form of the nerve- 

 elements. The nuclei of the cells were sometimes pushed 

 forwards towards the periphery by the intrusive elements. 

 In other cases the nerve-cells seemed entirely replaced by 

 masses of round indifferent corpuscles.. These changes 

 were seen even in isolated nerve-cells. The author points 

 Gilt the analogy of these changes to those described by 

 Popoff in enteric fever and injuries. 



With regard to the innocuousness of the milk derived 

 from rabid animals, there is a conflict of opinion. Cases, 

 however, are on record both of human beings and the 

 offspring of animals becoming affected through partaking 

 of milk secreted by hydrophobic and rabid subjects; but 

 many of these cases, it must be confessed, are involved in 

 doubt. 



Mr. Fleming, in his work on "Rabies and Hydrophobia," 



