306 The Management and Diseases of the Dog. 



" Of these observers, Dr. Sanderson points out that Dr. 

 Letzerich,* of Braunfels (Nassau), and Dr. Oertel.t of Mu- 

 nich, are most important. The former is the author of 

 several papers on diphtheria, the titles of which are given 

 in a note. These papers contain various observations re- 

 lating to diphtheria as it presents itself clinically, and serve 

 to illustrate the intimate association of the development of 

 microzymes in the affected parts with the morbid process ; 

 the author also records numerous experiments showing that 

 when the disease is communicated by inoculation, its 

 characteristics reappear in the infected animal, even those 

 ■which belong to its more remote complications. 



" Dr. Letzerich's facts lose much of their value, according 

 to Sanderson, from their not being set down with that sim- 

 plicity which ought to characterise all scientific writings. 

 His papers, moreover, contain a great deal of questionable 

 mycology, in which the patient reader is apt to lose himself 

 in his search after objective facts. 



" The M^moire of Dr. Oertel, published three years ago, 

 also embodies anatomical and experimental investigations 

 relating to the effect of inoculating animals with material 

 derived from the larynx in cases of diphtheritic laryngitis 

 in children. Like Letzerich, the author found that a 

 disease having well-defined pathological characteristics, and 

 in particular, associated with nephritis, could be produced 

 by such inoculation ; and further, that it could be commu- 

 nicated from one animal to another without losing any of 

 its distinctive features. He further showed that the disease 

 in question, whatever were the local peculiarities given to 

 it by the tissue in which it was ingrafted, was always a 

 mycosis ; in other words, that all the ' localisations ' of the 



* Letzerich, '' Beitrage zur Kenutnisf der Diphtheritis," " Virchow's 

 Archiv.," vols. xlv. p. 327 ; xlvi. p. 229; xlvii. p. 516. "Monographie . 

 der Diphtheric," Berlin, 1872. " Die Entwickelung des piphtherie- 

 pilzes," " Virchow's Archiv.," vol. Iviii. p. 303 (1873). 



t Oertel, " Experimentelle Untersuchungen iiber Diphtherie ; " 

 "Deutsches Archiv. fiir Klin. Med.," vol. viii. pp. 242 — 354. 



