3o8 The Management and Diseases of the Dog. 



" On an examination of the body, it was discovered that in 

 the swollen baggy part of the skin where the inoculations 

 had been made^ there was fibrous infiltration of the subcuta- 

 neous connective tissue, with haemorrhagicpatches of a bluish- 

 black or dirty light-red colour, that passed deep into the 

 muscles of the back. In the abdominal muscles attached 

 to the spine, as well as in the peritoneum, there were also a 

 few isolated patches, generally running into each other in 

 an irregular manner. In the connective tissue of this 

 region were many marked haemorrhagic patches, and they 

 were all related more or less to others in the connective 

 tissue surrounding the left kidney. This organ exhibited 

 on the infero-external portion, which was in contact with 

 the lumbar region, a circular, eroded, haemorrhagic spot, 

 about the size of a rather large pea. The liver was 

 reddish-brown in colour, and very much enlarged and 

 indurated. The spleen was also enlarged, very full of blood, 

 and its parenchyma softened. The heart was softened, and 

 its texture very light-coloured. The lungs were healthy, 

 but the stomach and intestines were somewhat swollen ; 

 the stomach was empty, and the small intestines nearly so ; 

 the large intestines contained a quantity of fluid faeces, but 

 no scybala. The right lumbar region was normal, and the 

 right kidney large and light-coloured. The bladder con- 

 tained a small quantity of muddy urine. 



" A colleague of Dr. Letzerich made a most careful and 

 interesting histological examination of the body, and found 

 at the seat of inoculation, in the wedge-shaped exudate 

 formed at the punctures and wounds, bacteria and plasma- 

 globules {plasma-kugelit) closely agglomerated, the latter 

 being in a finely granular condition. In a prepared section 

 of the skin it was noted that the sheaths of the hair in 

 various parts were full of bacteria, micrococci vesicles, and 

 plasma-globules. In the texture of the skin itself were 

 numerous masses of bacteria and plasma-globules, as well 

 as clusters of micrococci. In the vicinity of those muscles 



