246 Veterinary Medicine. 



and later pus, scybala, passed with tenesmus, but no sloughs and 

 little odor ; 2. Diphtheritic dysentery, with thin watery bloody 

 discharges having a pronounced cadaveric odor ; also tenesmus, 

 sloughs, and increasingly offensive smell ; 3. Amoebic dysentery 

 with frequent bloody mucus stools, tenesmus sloughs and fcetor, 

 but with distinct remissions or intermissions. With this latter, 

 amoebae are found abundantly and more so in the more acute cases 

 with alkaline stools. They are found in the fresh warm stools, 

 5 to 8 times the size of a red blood globule and oval, pyriform 

 or irregular in form, with nucleus and nucleolus. Kartulis and 

 Hlava succeeded in inducing dysentery in cats and dogs by 

 injecting pure culture of the amoeba, and the former testifies 

 that dogs in Egypt take the disease spontaneously and their stools 

 contain the same amoeba coli as is found in man. 



Cunningham who investigated the subject in India found 

 amoeba in the bowels of healthy men, and also abundantly in the 

 faeces of horses and cows, which have naturally the requisite 

 alkaline reaction. 



The mere presence of the amoeba therefore may not be sufficient 

 to cause the disease, but with the requisite predisposition and an 

 alkaline condition of the intestinal contents, it is manifestly an 

 important factor in the disease. 



Bacillus dysenteries (Shiga) a main cause of dysentery in Japan, 

 grows freely in weak alkaline bouillon at 37 ° C, produces potent 

 toxin in three weeks, . 1 cc. of which kills a Guineapig in 24 to 

 48 hours. The horse and rabbit are very susceptible to this toxin. 

 Allied forms, in other epidemics differ in fermenting sugars (man- 

 nite, maltose and saccharose) producing gas and indol, while 

 Shiga's bacillus does not. 



The causative microbes in other forms of dysentery have not 

 been identified, but under the requisite irritation and local debility 

 one can easily conceive of the ordinary bacterial ferments of the 

 intestine, concurring with others introduced from without, in de- 

 termining the morbid condition. With better hygiene the disease 

 is steadily diminishing in man and beast, though violent epizootics 

 (in cattle) still appear in connection with wars (siege of Belfort, 

 1870, Zundel), and carriage by sea in hot climates (Mediterranean 

 trade, Bouley). 



Symptoms. The disease sets in suddenly, yet prodromata may 

 occasionally be observed, such as dullness, languor, trembling over 



