1'R(k;ki':ssi\i-; 



ISSL'K CUANC.l'IS. 



179 



there is an increase in the number of cells composinL,'- them. 

 Union or fusion of buds or processes from different vessels re- 

 sults in anastomosis or inosculation. Tliese jjrocesses are thus 

 the forerunners of capillaries and by a dilatation and an increase 

 in the thickness of their walls due to formation of fUirous and 

 muscular tissue, arteries and veins are formed. The new vessels 

 produced in the repair uf an injury are invarialjly in excess of 

 the normal vascular rec|uirements of the part. The excess \'es- 

 sels in an injured area are obliterated h\ cicatrization. 



Connective tissue is usually completely regenerated. Con- 

 nective tissue is regenerated from pre-existing connective tissue 

 cells, wandering cells and endothelial cells. 



Mucoid connective tissue is not normally found in the adult 

 animal except in a modified form in the vitreous chamber of the 

 eye. Mucoid tissue is not regenerated, although it is possible 

 that other types of regenerated connective tissue are mucoid in 

 the beginning. 



Fibrous connective tissue is rapidly and completely 'regen- 

 erated. White fibrous connective tissue is frequently substi- 

 tuted for other tissues. The fibres in regenerated fibrous con- 



Fig. 103. — Fibrous Eegeneratii.n. 



nective tissue liave the same origin as those in normal fibrous 

 tissue. Regeneration of white fibrous tissue may be studied m 

 the union of the ends of a tendon after tenotomy. The space 

 between the ends of the tendon is filled with blood and lymjih 

 which escaped from the severed vessels. The pre-existing con- 

 nective tissue cells bordering the wound in the tendon, together 

 with wandering cells, begin proliferating within forty-eight 

 hours, their progeny being fil)roblasts. The fibroldasts produce 

 a tangled mass of fibrous connective tissue, and at the same time 

 there^'is vascularization of the extravasate which occupies the 

 space between the severed ends of the tendon, .\fter the ends 



