188 VETERINARY PATHOLOGY. 



tissues in wounds that heal by granulation is possible only in 

 very young- animals and in tissues not highly organized. 



To recapitulate, healing l)y second intention embraces sup- 

 puration, granulation, cicatrization, epithelization and substi- 

 tutiiin. 



In some individuals the formation of fibrous connective tis- 

 sue is cimtinuous and there is formed large masses of cicatrical 

 tissue known as keloids. Keloids are classified with neoplasms 

 by some authors. 



HYPERTROPHY. 



ETIOLOGY. 

 Aiitcii<ital. 



L'licqiiat pressure. 

 A 111 II io til adIiesiDiis. 

 Post-natal- 



Increased nutrition. 

 I iiereased function. 

 Internal secretion. 

 I liiiiinished pressure. 

 API'Il.lRAXCE. 

 Miicnisco/^ic. 

 M icrnscot^ic. 

 T/.V.S7 7; .IFfECTRP. 

 EEEECTS. 



H\"pcrtrop]n- litcralh- means excessive nutrition. Rv usage 

 the term has dime td mean, an abnormal increase in the size of 

 an organ or part. In a more restricted and definite sense, hy- 

 pertriiplu- is a term ap])lied to that condition resulting from an 

 abnormal increase in the size of tlie essential cells of the part. 

 Thus an increase in tlic size of the liver as a result of an in- 

 creased aniiiunt nf the interstitial tissue or an increase in the 

 size I if a kidne\- due to an accumulatidu nf an inflammatorv ex- 

 udate or oedematous transudate is not an hvpertrophv, al- 

 thougli sucli conditions ha\'e been called false or pseudo-hvper- 

 trophy. Tumors produce an increase in the size of the struc- 

 ture affected, 1nit this should not l)e confused with hypertrophy. 

 Hyperidasia is a condition resulting from aluiormal increase in 

 the number of the cells thougli it is difficult to differentiate 

 from hypertrophy. 



CtiMPEXS.XToiri- iMT'i-:R'tuopiiY is the name applied to that type 

 of li}']:)ertrophy caused by increased functional activity. Thus 

 an increased blood pressure maintained for some time induces 

 compensatorv hypertrophy of the heart. 



Concentric h\-pertr()piiy is a term denoting an hypertrophv of 



