206 



VETERINARY PATHOLOGY. 



Appearance. — Macroscopic. — Tissues affected with fatty infil- 

 tration are greasy or oily, more friable than normal, and paler in 

 color, the color being uniform throughout or mottled. The quan- 

 tity of blood in the fat varies, there being more, in general, in 

 tlie fat of young animals. Aluscular tissue in which there is a 

 fatty accumulation contains areas or strata of fat and strata of 

 muscular tissue. The dejjosition oi fat ma^' ])e so extensive in 

 muscular tissue of hugs that there is little e\-idence of muscle. 

 Sul)ser(jus accumulations (_)f fat mav be localized, gi\-ing the ap- 

 pearance of masses of fat, or it ma\' be accumulated diffusely 

 as thick layers i:f fat. In dogs and cats the excess fat is usually 

 deposited around the kidneys. 



Microscopic. — In the early stages of ph\'siologic fatty changes, 

 small droplets of fat are observed between and within the cells. 

 'I'he intracellular fat gradualljr mcreases and assumes the space 

 within the cell, the nucleus being crowded to the margin of the 

 cell and mav ultimateK- disappear. 



Fig-. IIJ. — Fatt.v Inliltratidn. liver, hog. showing infiltration of globules I'r. 

 perii>ln:r,\' of lotaule toward its cc-ntor. 



Tissue Affected. — All tissues are subject to fatty accumula- 

 tions, excepting the normal depositories, the liver being most 

 prone to the affection. 



Effects. — The influence of physiologic fatty changes is de- 

 pendent upon the extent of the condition and the duration of 



