Ri-;rR(i(;R|.:ssi\'i 



ISSL'I-: <ll Ai\(,I^S. 



n9 



les as lai-o-e as a black walnut. Alore rarely the colloid material 

 may have mfiltrated the tissue spaces and "become diffuse. Col- 

 loid varies in consistency from a watery to a jelly like mass, is 

 usually of a clear amber color, although it may be translucent 

 or of a deep mahogany tint. 



An affected tissue contains varialjle sized areas of li)alinc, 

 rather firm, amber or mahogany colored masses deposited ir- 

 regularly throughout the entire structure. 



Microscopic— The cells are noted to contain small droplets 

 of colloid material which is constantly produced and passed out 

 of the cells and accumulated in the acini, tubules, or intercelhi- 

 'ar spaces. Other entire cells are converted into a colloid 



Fiq- lis — Colloid Ocseneration, Tli>roitl Gland. 

 Colloid mntirial conipl.toly filling thi' acini of gland. 



mass. The conversion of a large number of cells intu cnlloid 

 material in one \-icinity produces colloid masses or the so-called 

 Colloid cysts. Colloid substance is homogeneous or slightly .gran- 

 ular and is stained, by acid stains. It assumes an orange color 

 when stained according to Van Giesen's method. 



Tissue Affected. — Epithelium is ])ro))a]:>ly the only tissue 

 in which colloid formation occurs. The thyroid gland is most 

 commonly affected. There is a degenerative change occurring 

 in carcinomata that is similar to the colloid formation althougli 

 it may be pseudomucin formation. McFarland states that col- 

 loid casts occur in the uriniferous tubules, in kidneys affected 

 \vith chronic inflammation. Ziegler regards the prostatic con- 

 cretions, of the human, that do not react to iodine, as colloid. 



