246 X'ETERINARY PATllOLOGY- 



(leposition in the tissue. Bild^pigmentation is designated hepa; 

 ttigcnuus pigmentation and the cunditiun produced is commonly 

 known as icterus or jaundice. Obstruction of the bile duct or 

 any of its radicles Ijy pressure, duodenitis, calculi, etc., will result 

 in retention of the generated bile which is later resorbed into 

 the blood. Destruction of considerable numbers of liver cells or 

 diminution of their function may possibly result in the retention 

 in the blood of those products that are normally converted into 

 bile, and thus produce a hematogenous icterus. E.xcessive pro- 

 duction of bile, as in acute tick fex-er, is frecjuentlv accompanied 

 bv resorption of some of the bile and its deposition throughout 

 the body, thus producing a generalized icterus. 



Bile staining is most e\'ident in the conjunctiva and ocular 

 sclera of the li\ing animal where it produces a lemon or greenish 

 yellow discolorization. If resorpti(jn of bile is very extensive 

 it may appear in tlie urine. In carcasses, biliary pigmentation 

 is mo-^t e\'ident in the adipose tissue, especially the subcutaneous 

 fat. although it is usually weU marked in the subserous fat and 

 may be detected in the lymph nodes, spleen, kidney and muscu- 

 lar struct'ires. 



The bile may be deposited in the cells or between the cells 

 as grecnish-yelldw amorphous granules. The granides are read- 

 iU- soluble in alcohol, hence they are best detected in frozen sec- 

 tions. 





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Fiff. loO, — Icterus afft'cting lymphatic tissur-. 

 Normal (issur. b. D(_']..osit of bilr i.igmunt. 



