NliCKOStS AXL) l)l£ATil. 



-C-J 



A part or organ separated from the remainder of the body 

 undergoes necrosis sooner or later, the time depending upon the 

 condition of the tissue and the temperature in which the sep- 

 arated portion is kept. Maceration and bruising produces ne- 

 crosis to a varying degree, depending upon the extent of the in- 

 jury. 



i:!l. — I'liiitOKT 



ill slmwiiit;- »<Tn(.is 



CJiciiiic substances. — Certain clicmic substances as phenol, 

 arsenic, mercury bichloride, strong solutions of the caustic alka- 

 lies and mineral acids, as well as the products of a large number 

 of bacteria, are tissue destroyers. Phenol abstracts water from 

 all cells to a sufficient extent -O destroy their vitality, and it pro- 

 duces a rapid disintegration of rerl blond cells. Arscnious tri- 

 oxide is frequently applied on tumors l^ecause of its erosive 

 action. Bichloride of mercury combines with the cell albumins, 

 forming albuminate of mercury, thus inhibiting the cell action, 

 and when all of the cell albumin is combined the cell is de- 

 stroyed. The caustic alkalies and mineral acids coagulate the 

 cell albumin or abstract the cell water, thus destroying them. 

 The Bacillus necrophoroiis produces chemic substances that 

 cause coagulation of the cell protoplasm (coagulation necrosis). 



