NECROSIS AND DEATH. 



OClj 



there was evidence of pancreatic lesions, as inflammation, hem- 

 orrhage and atrophy was noted in one case. Recently it has 

 been suggested that this condition is caused by disturl^ances of 

 the islands of Langerhan. 



The areas affected are at first soft and spong\-, but later be- 

 come more or less calcareous as a result of combination of lime 

 salts with the free fatty acid. 



Fatty necrosis usually involves the omental fat, and espe- 

 ciallv that in close proximitv to the pancreas, though all fatly 

 tissue is subject to this condition. 



In gross appearance the involved portions are dull, lusterless, 

 opaque, slightlv raised, usuallv circumscril)ed areas, of a vellow- 

 ish white color. If the lesions are ad\-anced, calcareous granules 

 may be observed by palpation. In microscopic section the cells 

 of the affected areas may contain needle-like crystals, or the cell 

 substance mav appear as a granular mass. 



o. Focal necrosis. — In certain infective diseases it has been 

 noted that small foci of the various parenchymatous tissues un- 



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Fig. 131 



-A necrotic tiiherfle; lung, xL'.^iO, Slicnvirif; ini-rnUf ciitti- 

 by small round cells, cpithcloid cells, and leucocytes. 



