300 



VETERTNARV P.VTHOLOGY. 



a limited amount of intercellular substance. The cells may be 

 round, spindle, or m3'eloid, and the intercellular substance may 

 be mucoid, fibrous, cartilaginous or osseous. The cells contain 

 a large centrally located ovoid nucleus, occupying practically 

 the entire cell body. Mitotic figures are common in rapidly 

 growing sarcomata. Frequently there are multipolar mitotic 

 figures indicating the possible division of a cell into three or 

 more daughter cells. Karyolysis or nuclear fragmentation is 

 well marked in those cells that are centrall)^ located in the tumor, 

 that, is, in degenerating centres, and in cells of sarcomata that 





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Fij-, 1:,-, Section of tumur, showing mottled appearance, a result of Necrotic cent 



