320 



\ETi:l-;lX.\KV l>ATHOL(;GV. 



invariably fijund upon the skin and constitutes the growtlis ordi- 

 narily known as warts. Thev may also be soft, and are then 

 found upon mucous, serous or synovial membranes, in which 

 case the covering epithelium is not cornified. Hard papillomata 

 cir warts niav appear as tabulated masses, as fungoid growths or 

 as a mass of villi. Any of the above forms may have a smooth 

 surface or be fissured with a very irregular surface. They vary 

 in size from a millet seed to an apple. They may be single but 

 are more fre<:|uentl_v multiple. 



Microscopically, the_v are composed of adult epithelium and 

 of fibrous connective tissue in varying proportions. They sug- 

 gest the structure of cutaneous papillae. In fact, they have been 



_ ioiirrne 



Fig, 174, — t^fctirm or rapillonia from OeNopliaj^iis of cow, showing 

 bands of stroma oover^'d by epitholium. 



described as hypertrophied papillae. The fibrous tissue is the 

 supporting structure or framework of the tumor and contains 

 the bliiod vessels and nerves when they are present. The epi- 

 thelium is the covering mantle of the fibrous tissue. In the hard 

 papillomata the epithelium is stratified and the surface cells are 

 cnrnificd. In soft papillomata the epithelium may be single or 

 stratified but the surface cells are not cornified. The proportion 

 of fibrous tissue and epithelium in papillomata may be the same 



