S2 PHARMACY 



In the preparation of fluidextracts by either process A, B, or C 

 the rate of percolation must be perfectly controlled and, for the 

 quantities directed in the formulas of the Pharmacopoeia (1000.0 

 Gms.) the rate of flow should not exceed ten drops per minute, until 

 the reserve percolate is collected and twenty drops per minute there- 

 after. 



DIRECTIONS FOR THE DIFFERENT TYPE PROCESSES 



Type Process A. Moisten required amount of the powdered 

 drug with a sufficient amount of the prescribed menstruum to render 

 it evenly and distinctly damp and to maintain it so, after macerating 

 for six hours in a tightly covered container. Then pack it in a 

 cylindrical percolator and add enough of the menstruum to saturate 

 the powder and leave a stratum above it. When the liquid begins to 

 drop from the percolator, close the lower orifice, and, having closely 

 covered the percolator, macerate for forty-eight hours. Then allow 

 the percolation to proceed slowly, gradually adding more menstruum 

 until the drug is exhausted. Reserve the first eight hundred and 

 fifty mils of the percolate (unless otherwise specified in the for- 

 mula) ; recover the alcohol from the remainder and concentrate the 

 residue to a soft extract at a temperature not exceeding 60° C. ; dis- 

 solve this in the reserved portion, mix thoroughly, and finally add a 

 sufficient quantity of the menstruum to obtain one thousand mils or 

 the volume determined by calculation or directions. 



Type Process B, Moisten one thousand grams of the pow- 

 dered drug directed with a sufficient quantity of the prescribed Men- 

 struum I to render it evenly and distinctly damp and to maintain it 

 so after maceration for six hours in a tightly covered container. 

 Then pack it in a cylindrical percolator, add the remainder of Men- 

 struum I, and when this has just disappeared from the surface, 

 gradually add Menstruum II, constantly maintaining a stratum of 

 liquid above the drug. 



When the liquid begins to drop from the percolator, close the 

 lower orifice, and, having closely covered the percolator, macerate 

 for forty-eight hours, and then allow the percolation to proceed 

 slowly, gradually adding Menstruum II until the drug is exhausted. 

 Reserve the first eight hundred and fifty mils of the percolate (unless 

 otherwise directed in the formula) ; recover the alcohol from the 

 remainder and concentrate the residue to a soft extract at a tem- 

 perature not exceeding 60° C. ; dissolve this in the reserved portion, 

 mix thoroughly, and finally add a sufficient quantity of Menstruum 

 II to obtain one thousand mils, or the volume determined by calcu- 

 . lation from assay. 



Type Process C. Divide one thousand grams of the powdered 

 drug directed into three portions of five hundred grams, three hun- 



