CAMPHORA MONOBROMATA 89 



Coryza of Dog. 



5 Camphorse gr. xij 



Extract! Opii gr. iij 



Ammoiiii Carbonatis gr. xxiv 



M. Fiant Capsulse No. 12. 



Sig. One every two hours. 



CAMPHORA MONOBROMATA 



Monobromated camphor is obtained by the union of camphor 

 with bromine in the presence of heat. It occurs as colorless pris- 

 matic crystals, needles or scales; it has a mild camphoraceous odor 

 and taste; slightly soluble in water and glycerin, freely soluble in 

 alcohol, ether and chloroform. Doses. D. grs. ij — x; 0.13 — 0.6. 



Monobromated camphor in small doses is sedative to the nervous 

 system. It has been recommended as an antispasmodic and anaphro- 

 disiac in man and the small animals, but its results are somewhat 

 questionable. 



Borneol Camphor. This resembles the action of camphor in 

 many respects, but does not stimulate the heart and finally depresses 

 the nervous system. It has no therapeutic indications in veterinary 

 medicine. 



OTHER CIRCULATORY STIMULANTS 



Ether. This drug ordinarily has little influence upon the heart, 

 but through its local irritant action inay reflexly increase the pulse 

 and slightly raise blood pressure. It may be given subcutaneously 

 in doses about one-half of the oral ones, and is useful in sudden heart 

 failure, as in shock, poisoning or collapse. 



Adrenaline. If this is given intravenously in therapeutic doses 

 the pulse is slowed and blood pressure raised. The slowing of the 

 pulse is due to stimulation of the cardio-inhibitory center in the 

 medulla, while blood pressure is raised by direct constriction of the 

 peripheral vessels, together with its direct stimulating action upon 

 the heart. These actions take place promptly but are of short dura- 

 tion. Sometimes a solution of adrenaline 1 — 50,000 in normal salt 

 solution is used intravenously in cases of shock resulting from injury 

 or operation. See page 98. 



Nitrites. To this group belong nitroglycerin, amyl nitrite, and 

 sodium nitrite. All act similarly but differ in rapidity and per- 

 sistence of action. Amyl nitrite is most rapid and least persistent, 

 while sodium nitrite is least active and most persistent. All the 

 nitrites accelerate the heart, probably by action upon the vagus center, 

 and. lower blood pressure by depressing the muscles of the arteries, 

 causing vasodilation. Their chief value does not depend upon any 

 direct action upon the heart but on the fact that they dilate the 

 peripheral vessels and consequently lessen the work of that organ by 



