122 ANTIPYRETICS 



Internally. 1. As a specific for acute muscular or articular 

 rheumatism. Here one of the salicylates is to be preferred. They 

 lessen pain and swelling, lessen the danger of cardiac complications, 

 and shorten the attack. The manner of action of the salicylates in 

 these conditions is not well understood, but it is believed or suspected, 

 at least, that they have a specific action against the infective agent. 

 Fair sized doses should be given every two or three hours until im- 

 provement is seen and then less often. The salicylates have little 

 influence upon chronic rheumatism except to check acute attacks of 

 the disease. 



2. Salicylic acid or the salicylate of sodium is often of consid- 

 erable sendee to check excessive fermentation in the digestive tract, 

 especially in gastric fermentation of the horse. The acid is usually 

 preferred for this purpose and is given in capsule in 4 to 6 dram 

 doses. 



3. Antipyretics. These agents have been iised as antipyretics 

 but they do not compare very favorably with those of the previous 

 group. 



For Acute Moist Eczema. 



B Acidi Salicylici. 



Acidi Tannici aa 5. 



Alcoholis q. s ad. 100. 



M. Ft. Sol. Apply to affected parts. 



B Acidi Salicylici gr. xv 



Zinci Oxidi. 



Amyli aa 3 ii 



Petrolati q. s ad. 3 i 



M. Ft. Pasta. 



For ring worms, etc. 



PHENYLIS SALICYLAS — PHENYL SALICYLATE 



Synonym. Salol 



Phenyl salicylate is composed of 60 parts of salicylic acid and 40 

 parts of phenol. It is a white powder, of aromatic odor and taste, 

 sparingly soluble in water, soluble in alcohol, ether and oils. 



Doses. H. 3ij— viij; 8—30. D. gr. ij— xv; 0.13—1. 

 Daily doses, gr. xv — ^Ix; 1 — 4. 



External and Local Action. This resembles the other salicy- 

 lates and in addition is somewhat of a deodorant. 



Digestive System. Salol is insoluble in the gastric juice and 

 consequently passes into the intestines unchanged, where it is broken 

 up by the alkaline pancreatic juice into its constituents, which are 



