MENTHOL 195 



venously, while the intracerebral injections produced a state of gen- 

 eral inhibition. Both the intravenous and subcutaneous injections 

 produced a complete muscular relaxation in tetanus, lasting often as 

 long as twenty-four hours. Meltzer later used the intraspinal 

 method (1 mil of a 25 per cent, solution to each 25 pounds of 

 weight) for several operations and as a treatment for tetanus. In 

 the latter condition, however, although the relaxation may last for as 

 long as twenty-four hours, there was no effect upon the high tem- 

 perature of this disease and the patients died from exhaustion, with- 

 out there being any gain in the reduction of the mortality. This 

 drug has never gained any prominence as a local or general anes- 

 thetic in veterinary medicine and is being discarded or superseded 

 by other drugs in humam medicine. 



Menthol. Menthol is a stearopten obtained from oil of pepper- 

 mint. It occurs in the form of colorless prismatic or acicular crys- 

 tals, having a mint-like odor and taste. It is slightly soluble in 

 water, but freely soluble in alcohol, ether and chloroform. 



Doses. H. grs. vijss — xv; 0.5 — 1. D. gr. ss — ij ; 0.03 — 

 0.13. 



Action and Uses. Menthol is a local anesthetic and antiseptic. 

 It liquefies when triturated with camphor, thymol or phenol. 



It is used as a local anesthetic or anodyne and antiseptic in dust- 

 ing powders, ointments or solutions. One part of menthol to ten of 

 olive oil makes a useful application to burns. Internally it is a 

 carminative and analgesic. 



IJ Mentholi. 



Eucalyptoli aa 3 j 



Alcoholis 3 ij 



Liq. Oresolis Comp ^ ^. . . 



Aqu£e q. s. . . . .' ad. S viij 



M. Ft. Sol. 



Sig. One-half ounce in hot water as an inhalant. 



For Pruritis. 



5- Mentholi ^ \ 



Alcoholis q. s *"• ° 3 



M. Ft. Sol. 



Sig. Apply to parts as necessary. 



Ointment for Pruritis. 



5 Mentholi \^? 



Olei Olivse V • f ^• 



Petrolati q. s '-ad. 3 ij 



M. Ft. Unguentum. 

 Sig. Apply as necessary. 



