ARECOLINE HYDROBROMIDE 



211 



Therapeutics, 1. As a cathartic for all those conditions in 

 horses requiring a rapid evacuation of the bowels: colic, impactions, 

 etc. It is often useful to stimulate contractions of the rumen in 

 cattle. It is equal if not superior to eserine or pilocarpine or a com- 

 bination of these drugs for this purpose. It can be given in small 

 doses repeated once or twice at 15 to 30 minute intervals. 



2. As a specific for laminitis in the horse. In this disease it has 

 given especially good results. The animals are usually able to return 



Fig. 20. Arecoline and Atropine. 

 Horse. The short tracing to the left is the normal. The left vertical arrow 

 shows when the arecoline was injected. Note the fall in blood pressure. 

 The second vertical shows when the atropine sulphate was injected. Note 

 tlie rise of blood pressure and more rapid heart beat. (Tracing made by 

 Dr. P. A. Fish.) 



to work much sooner than under any other treatment. It should be 

 given in daily doses or twice daily (morning and night) of V' — 1 

 grain along with other treatment. 



3. In azoturia. Some clinicians report good results from the use 

 of this drug in azoturia. It is not to be regarded as a specific but as 

 a rapid eliminant or cathartic. Other treatment should not be 

 neglected. 



'4. Myotic. Solutions of % to 1 per cent, may be used as a myotic 

 to counteract the action of atropine or to use alternately with atro- 

 pine in iritis to prevent or break up adhesions of the iris. It may 



