IPECACUANHA — IPECAC 



Permanent solution. 



R Apomorphinse Hydrochloridi gr. iij 



Solve in aqua dest 3 v 



Ad Acidi HydrocMoride ni ij 



M. Ft. Sol. This is a 1 per cent, solution for hypodermic use. 



IPECACUANHA 



Synonym. Ipecac 



Parts Used. The dried roots and a small portion of the stem 

 of Cephaelis Ipecacuanha (Kio Ipecac) or C acuminata (Cartagena 

 Ipecac). 



Constituents. Ipecac contains three alkaloids -which contribute 

 to its actions, one of which is of relatively, little importance. These 

 are cephwline, to which the emetic action is due for the greater part ; 

 emetine, which was so named when it was supposed to be the only 

 active constituent present; and psycJiotrine, which is unimportant. 

 The different alkaloids have not been studied in great detail, and 

 we are not able to determine in every case to which we may attribute 

 a given action of the crude drug. 



Emetine is known to be less emetic than cephseline, but commer- 

 cial specimens of emetine certainly cause emesis whether adminis- 

 tered by the mouth or intravenously. ' 



Preparations and Doses. 



Fluidextractum Ipecacuanhw, or powdered root. Expector- 

 ant. H. 3j— ij; 4.-8. D. gr. %— %; 0.01—0.05. 

 Emetic. D. gr. v — ^xxx; 0.3 — 2. 



Syrupus Ipecacuanhw. Expectorant. D. TIXv — xxx; 0.3 — 

 2. Emetic. D. 3ss — iv; 2. — 15.0. 



Pulvis Opii et Ipecacuanhw (Dover's Powder). See Opium 

 p. 137. Expectorant. H. 3iv — ^viij ; 15 — 30. D. gr. ij 

 — x; 0.13—0.6. 



*Tinctura Opii et Ipecacuanhw. Expectorant. Same as 

 for above. 



Action. 



Externally and Locally. Ipecac is a powerful local irritant. 

 The prolonged application or rubbing upon the skin causes much 

 irritation, which may pass to vesication, pustulation or ulceration. 

 It is also especially irritant to the mucous membrane of the respira- 

 tory tract. 



Digestive System. Ipecac, in small doses, stimulates the 

 stomach, increases the salivary and gastric secretions and serves as a 

 bitter or stomachic. 



Large doses are powerfully irritant and emetic, the emesis being 

 produced largely by local action on the stomach, but there is reason 



* Unofficial. 



