276 SPECIFICS FOR THE ALIMENTARY TRACT 



combined with. Aspidium. Turpentine is too irritating to the stom- 

 ach and intestines to be of service in canine work unless properly- 

 diluted or combined with other drugs. See after Chenopodium. 



Chloroform, Thymol and Betanaphthol have not been used suffi- 

 ciently to determine their value as tsenicides. 



ROUND WORM GROUP 



Many of the remedies used against tapeworms are also effective 

 for the round varieties. The same dietary measures and subsequent 

 purging should be followed as outlined under tapeworms. 



* SANTONICA 



Synonyms. Levant Wormseed, Cinse Mores 



Parts Used. The dried unexpanded jflower heads of Artemisia 

 pauciflora, a perennial shrub of Turkestan. The dose for the dog 

 is 10 — 60 grains but the use of the crude drug has been practically 

 abandoned in favor of its glucoside, santoninum. 



SANTONINUM 



Synonym. Santonin 

 Properties. This occtirs as colorless crystals when first pre- 

 pared but assumes a yellowish color on exposure to light. This, 

 however, does not seem to affect its activity to any appreciable ex- 

 tent but should be avoided by keeping santonin in amber colored 

 bottles. 



Doses. H. 3 j— ij ; 4.-8. D. gr. j— iij ; .065—0.2. Cat. 

 %o— %; 0.006—0.03. 



Preparation. * Trochisoi Santonini. Each contains % grain 

 of santonin. 



Action. Santonin in moderate doses has no appreciable physio- 

 logical action upon the host. It is probably the best remedy we 

 possess against round worms but is not so effective for the tape or 

 hook worms. The action of this drug is not well understood. When 

 worms are placed in solutions of it they do not die but move more 

 vigorously. It is generally believed to be very irritating to them 

 but not necessarily fatal and that santonin drives the worms to the 

 large intestine from which they may be easily removed by a purga- 

 tive. They are often expelled in a very active condition. 



Santonin is practically insoluble in water but undergoes some 

 change in the digestive tract so that part is absorbed and in some 

 cases peculiar conditions are produced even by small doses. The 

 most common symptoms following its administration in man is a 

 disturbance in vision (xanthopsia) or yellow vision, so that every- 



* UnoflRcial. 



