452 GERMICIDES — DISINFECTANTS 



Bacelli's Treatment for Tetanus. 



^ Phenolis. 



Glycerini aa. S j 



Aquae q. s ad. 3 xxiv 



M. Ft. Sol. 



Sig. Three ounces subcutaneously every two to four hours. 



THE PHENOLSULPHONATES — SULPHOCARBOLATES 



The principal phenolsulphonates are those of Calcium, Zinc and 

 Soda. 



Sodii Phenolsulphonas is obtained by dissolving phenol in sul- 

 phuric acid, and converting this product into a sodium salt. It 

 occurs as colorless, transparent, rhombic prisms or crystalline gran- 

 ules; odorless and having a cooling, saline bitter taste. Soluble in 

 about 4: parts of water, 140 of alcohol and 5 of glycerin. 



Dose. H. and C. 3j — ^viij ; 4. — 30. Dog, gr. iij — xv; 

 0.3—1. 



Zinci Phenolsulphonas occurs as a colorless, transparent, 

 rhombic prisms or tubular crystals or in granular form; odorless, 

 and having an astringent, metallic taste. Soluble in about 2 parts 

 of vyater and alcohol. 



Dose. One-haK that of the" sodium salt. 



Calcii Phenolsulphonas occurs as white or faintly pinkish- 

 white almost odorless powder, having an astringent, bitter taste. 

 Easily soluble in water and alcohol. 



Doses. Same as for the sodium salt. 



Action. These salts act like carbolic acid but are practically 

 nontoxic. Sodium and calcium phenolsulphonates are used as in- 

 testinal antiseptics but theoretically are of doubtful value because 

 they are excreted unchanged. The zinc salt is astringent as weU 

 as antiseptic and is therefore used when a combination of these 

 actions is desired. Just how much they act as antiseptics cannot 

 be stated, but clinical experience points to their usefulness. It has 

 been recommended that they be given in solution for action upon 

 the stomach, and in keratin coated pills for action upon the intes- 

 tines. They are usually given, however, in the form of compressed 

 tablets, either coated or uncoated. They are frequently combined 

 as in the following prescription : 



B Zinci Phenolsulphonatis 1 part 



Calcii Phenolsulphonatis. 



Sodii Phenolsulphonatis aa. 2 parts 



M. Pt. Pulver. 



5 grains to a dog every 3 to 6 hours. 30 to 60 grains to the horse or 

 cow. 



