GUAIACOLIS CARBONAS — GUAIACOL CARBONATE 455 



GUAIACOL 



This is the chief constituent of creosote, from which it is ob- 

 tained by fractional distillation, or it may be prepared synthetically. 

 It occurs as a crystalline solid or oily liquid of unpleasant aromatic 

 odor and taste. It is slightly soluble in water but soluble in alcohol, 

 ether and glycerin. It unites with acids to form crystalline com- 

 pounds. 



Doses. Twice those of creosote. 



Action and Uses. Guaiacol acts similarly to phenol and creo- 

 sote. Tt is a powerful antipyretic if applied to the skin and evap- 

 oration is prevented, but is very depressant and transitory in action. 

 It has been recommended internally in the same group of diseases as 

 creosote. Quitman recommends it in dram doses in water, repeated 

 in from -J?^ to 2 hours if necessary, in edema of the glottis. It is 

 claimed that guaiacol will shorten the period of resolution in pneu- 

 monia of horses from 2 to 3 days. 



GUAIACOLIS CARBONAS — GUAIACOL CARBONATE 



Synonym. Duotal 



This product is obtained by the action of carbonyl chloride on 

 the sodium salt of guaiacol. 



It occurs as a white crystalline powder, of faint odor and taste. 

 It contains 91 per cent, of guaiacol, is insoluble in water, slightly 

 soluble in alcohol, glycerin and oils. It is claimed to be less toxic 

 and better borne than guaiacol, since it is odorless and tasteless. It 

 is used as a substitute for guaiacol in doses about double those of 

 that drug. 



Pneumonia of Horse. 



5 Guaiacolis 5 ij 



Glycerini S iv 



Alcoholis q. s ad. S xvj 



M. Sig. One ounce every three hours. 



Chronic Cough, Horse. 



B Guaiacolis 5 iv 



Olei Lini O. ij 



M. Sig. One to two ounces three times daily. 



Subacute Bronchitis, Dog. 



B Strychninse Sulphatis . . : gr. % 



OodeinsB Sulphatis gr. ij 



Guaiacolis Carbonatis gr. xxx 



Terebeni m xxx 



M. Pone in Capsules No. XXIV. 



Sig. Two capsules every 4 hours. 



