METHYLENE BLUE — TRYPAN BLUE 461 



not be confused with methylene blue. Pyoktanin blue occurs in the 

 form of small indigo-colored crystals, slightly soluble in water, freely 

 soluble in alcohol. 



Action and Uses. This preparation is slightly astringent, an- 

 tiseptic and analgesic. It is very useful in suppurations of the eye, 

 conjunctivitis, etc., in solutions of from 1 — 500 to 1 — 1000 in water. 

 It may be used on open wounds, upon galls, etc., in the same strength 

 solution in either alcohol or water. It is a favorite remedy of 

 horsemen for galls and chafes, upon which it may be used in alco- 

 holic solution or in the form of an ointment. Pyoktanin blue colors 

 the part a deep purple, but this may be removed by rubbing well 

 with soap and water and washing with alcohol. It is- not used inter- 

 nally in veterinary medicine. 



Pyoktanin yellow occurs as a yellow powder. It resembles the 

 previous variety but is weaker. 



Purulent Conjunctivitis. 



B Atropinse Sulphatis gr. ij 



Pyoktanin Blue gr. j 



Aquae q. s ad. 5 j 



M. Ft. Sol. 



Sig. A few drops in the eye three or four times daily. 



For Scratches, Hobble Chafes, etc. 



IJ Pyoktanin Blue gr. j 



Zinci Oxidi 3 j 



Petrolati 5 ij 



Tineturse lodi 3 ss 



M. Ft. Unguentum. 



Sig. Apply to parts. 



METHYLTHIONINE CHLORIDUM — METHYLENE BLUE 



Methylene blue is antiseptic and analgesic. It is eliminated to 

 a great extent by the urine and milk and has been used as a urinary 

 antiseptic. During its excretion it colors the urine green. On 

 account of its elimination through the mammary gland some prac- 

 titioners have employed it in mastitis with considerable success. 

 Kich recommends it in infectious abortion of cattle in daily doses of 

 10 grams in capsule or upon the ensilage for 4 or 5 weeks as early 

 in pregnancy as possible. He also employs it as a uterine douche 

 in the same condition, in the proportion of 10 grams of pyoktanin, 

 30 grams of salt, to a gallon of water. He has given as high as 

 4 ounces daily. 



* Trypan Blue. Trypan blue is a complex substance derived 

 from toluidine and amidonaphtholsulphonate of sodium. It has been 

 used with good results in the treatment of piroplasmosis of animals, 

 especially of cattle and dogs. JSTuttall used a 1 to 5 per cent, solu- 



