242 KENNEL DISEASES. 
about the twelfth day ; hence the stops are recommended, that any ill effects of 
the drug may pass off before the administration is resumed. 
If under this treatment the chorea is not cured, the same system might, in 
the course of two or three weeks, be employed the second time. 
Given as advised, unpleasant or poisonous symptoms are not likely to follow 
the use of arsenic in large doses; but if any appear, manifestly the medicine 
should be at once stopped. 
The most notable of such symptoms is paralysis of the hind legs. Other 
indications of poisonous effects are, redness of the eyes, pallor of the lining of 
the mouth and covering of the tongue, stiffness in movements, tendency to 
spasms, gastro-intestinal irritation, with vomiting, pain and diarrhea. 
In some cases treatment by the sulphate of quinine promises rather better 
than any other ; the dose being two grains for a pup over eight months old and 
of medium size ; three grains if of largest breed; one grain if about the size of 
fox terrier ; and one-half a grain if a toy. 
These doses should be given three times daily for about three weeks, unless 
the twitching sooner yields, or symptoms of ill effects are manifested. 
Quinine in such doses might lessen the hearing power, but it is not likely 
to do so. 
The nitrate of silver has been strongly recommended by some, and it has 
even been claimed that it is a specific for chorea. Although it has acted well in 
occasional cases, to call it a specific or sure cure for the disease is going much 
too far. 
Rightly used it can do no harm, and it is certainly worthy a trial in the worst 
cases. Granules of various strength can be obtained from druggists, and the 
proper doses are as follows: For the largest breeds, one-half a grain; medium 
size, as setters and pointers, one-fourth of a grain ; fox terriers and the like, one- 
eighth of a grain ; toys, one-twelfth of a grain. 
One granule should be given in the middle of the forenoon, and another in 
the middle of the afternoon ; and the use of the drug be persisted in for at least 
a month. 
While it is being given it will generally be advisable to administer a tonic, 
for the purpose of sustaining or increasing the strength, and adding vigor to the 
nervous system. Pills composed as follows should therefore be obtained : 
Sulphate of quinine, one drachm; dried sulphate of iron, one drachm. To 
be made into sixty pills. One to be given morning and night, with the break- 
fast and supper. 
These pills are right for medium size breeds. They should be one-half 
stronger for largest breeds; one-half weaker for fox terriers and the like; while 
only one-fourth as strong for toys. 
Cimicifuga or black snake-root is considered by some an efficient remedy 
for chorea, but, like the iodide of potassium, which also has advocates, it would 
