30 ANTISEPTIC TREATMENT OF WOUNDS. 
the use of sublimate has to be taken is due to the different 
individual predispositions toward mercurial preparations, pro- 
ducing in some cases eczemas, in another intoxications, while 
a third one will not be affected whatever. That much of this 
is exaggerated is proven by the successful results of VON 
BERGMANN, KUEMMELL, SCHEDE and MIKULICZ; 
the latter even in laparotomy washes out the peritoneal cavity 
with a 0.5 per cent. solution of sublimate. KROENLEIN 
uses sublimate (1:1000-3000) in wounds of the rectum, ab- 
domen, and in empyema without apparent toxic effects. In 
veterinary surgery the condition is different. The fear of the 
toxic effect of sublimate on our domesticated animals, and 
especially ruminants, is groundless, of which facts TRIN- 
CHERA especially makes mention. 
I used for the past three years in all surgical operations, as 
well as for the irrigation of all infectiously diseased mucous 
membranes (nose, mouth, vagina, uterus), only sublimate as 
an antiseptic, and must acknowledge that even in ruminants 
I did not notice any disadvantageous effects. The experi- 
ments of DOLERIS and BUTTE, who operated on the mu- 
cous membranes and fresh wounds of dogs, rabbits and guinea 
pigs with sublimate water I:1000) have proven that its use on 
mucous membranes is entirely free from danger; but deep 
wounds have to be treated somewhat more carefully. Unless 
the injurious effects of a 1 per cent. solution of sublimate is 
doubtlessly proven in the treatment of wounds of our domes- 
ticated animals, I consider the fear of the virulence of sub- 
limate, in external applications as prejudice. Later on I will 
have opportunity to illustrate with examples that sublimate is 
not dangerous. 
Amongst the numerous preparations of sublimate used in 
surgery the following are recommended as practical: 
(a) Sublimate triturates (ANGERER) are made by a com- 
pression of hydrargyrum bichloridum and natrium chloratum 
equal parts and on account of their convenient form 20 tablets 
can be carried in a test tube in the pocket without incon- 
venience, and owing to their solubility they are extraordinarily 
suitable for the practical veterinarian. 
