MATERIA MEDICA AND THERAPEUTICS. "JJ 



glycogenic functions of the liver. In toxic doses it causes two 

 different sets of symptoms. 



ist. Gastro-enteritis with shivering, retching, vomiting, 

 thirst, straining, purging, with blood stools, violent colicky pains, 

 quick weakened cardiac action, suppressed or bloody urine, strong 

 and hard pulse at first, but gradually gets small and weak, 

 reduced temperature, general oedema, delirium, collapse, coma 

 and death. 



2nd. In the nervous form the first thing noticed is pro- 

 found coma, like that of opium narcosis. Coma comes on sud- 

 denly without any gastro-intestinal symptoms. 



Chronic Arsenical Poisoning.* — Is common around tin and 

 copper smelting work. The symptoms are indigestion, thirst, 

 wasting, chronic disease of joints and bones, the knee joints 

 swell, the animal gets lame, and hide-bound, hair falls off, skin 

 gets scurfy, teeth get black and fall out and necrosis of the bones 

 occurs. 



POST-MORTBM APPEARANCES. 



■ Stomach inflamed, mucous membrane reddened, softened, 

 thickened and ulcerated in patches, ecchymosis. Same is formed 

 in the intestines, according to the size of the dose. 



Lungs congested, mucous membrane reddened. 



Genito-urinary organs congested and inflamed. 



Fatty degeneration of intestinal organs, especially liver and 

 kidneys, same as in phosphorus poisoning. 



In chronic poisoning the body becomes dry and mummified 

 (embalmed), general fatty degeneration. 



BITTERS. 



Bitters are divided into simple and aromatic. 



The aromatic bitters contain tannic and gallic acids, besides 

 aromatic constituents, and are therefore more or less astringent. 



Simple bitters contain no tannic and gallic acids, and can be 

 combined with iron. 



The special bitters eucalyptus, hydrastis, cinchona, etc., will 

 be treated of separately. 



