MATERIA MEDICA AND THERAPEUTICS. 141 



besides it is a powerful antiseptic and promotes the healing of 

 wounds. Used as an ointment it is very effective in parasitic 

 skin diseases. (10 to 25 per cent.) 



naphTol. — Same action and uses as naphtalin, but the dose 

 is only J4 as much. Naphtalin is preferred in veterinary practice. 



EXALGIN. 



Occurs in colorless crystals, odorless, tasteless, slightly solu- 

 ble in water and freely so in alcohol. 



It is a benzol derivative allied to phenacetin. 



Actions. — Powerful anodyne, nerve sedative, slightly anti- 

 septic and distinctly antipyretic, large doses cause convulsions, 

 dyspnoea, stupor and death. 



Uses. — It is the very best drug for chorea in dogs ; for aver- 

 age size dogs commence with 1 gr. 3 times a day. for 3 days, then 

 2 grs. 3 times a day for 3 days, then 3 grs. 3 times a day and 

 keep up the 3 grs. 3 times a day. Dose for man 2 to 8 grs. 



In addition Fowler's Solution of Arsenic should be given 

 in increased doses until the fullest extent of tolerance is reached. 



. ANTIPYRINUM— ANTIPYRIN. 



A whitish powder, soluble in equal parts of water by weight ; 

 best administered alone. 



Dose. — Horse, 1 to 3 drs. ; sheep, y 2 to 1 dr. ; cattle, 2 to 4 

 drs.; d^s, 1 to 5 grs. 



Actions. — Powerful antipyretic, anodyne and local anaesthetic, 

 antiseptic, cardiac depressant ; it reduces temperature very quick- 

 ly, usually within y 2 hour and the effects continue 2 or more 

 hours. It can be administered by the mouth, hypodermicaily or 

 intratracheally ; as an antipyretic it diminishes oxidation, and 

 promotes heat loss by dilating the cutaneous vessels, but more 

 probably by depressing the activity of the calorefacient centers. 



Uses. — Used in high fever where the temperature must be 

 reduced quickly, as in sun-stroke and acute rheumatism ; in man 

 a solution of antipyrin from 10 per cent strength up, is sprayed 

 into the nostrils for hay-fever. Acetanilid is a better, safer and 

 much cheaper drug,. .for febrile diseases. 



